Centromere Clustering: Where Synapsis Begins
نویسندگان
چکیده
Centromeres congregate into a large cluster called the chromocenter during Drosophila oogenesis. Two recent studies now define a function and a genetic basis for this remarkable structure.
منابع مشابه
Synaptonemal Complex-Dependent Centromeric Clustering and the Initiation of Synapsis in Drosophila Oocytes
The pairing of homologous chromosomes and the intimate synapsis of the paired homologs by the synaptonemal complex (SC) are essential for subsequent meiotic processes including recombination and chromosome segregation. Here we show that the centromere clustering plays an important role in initiating homolog synapsis during meiosis in Drosophila females. Although centromeres are not clustered pr...
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عنوان ژورنال:
- Current Biology
دوره 21 شماره
صفحات -
تاریخ انتشار 2011